The first RPOC system based on femtosecond lasers and SRS/TPEF microscopy
M.G. Clark, G. Gonzalez, Y. Luo, J. Aldana-Mendoza, M.S. Carlsen, G. Eakins, M. Dai, and C. Zhang*. "Real-time precision opto-control of chemical processes in live cells". Nature Communications, 13, 4343 (2022). Link
CW-RPOC technology
B. Dong#, S. Mahapatra#, M.G. Clark, et al. and C. Zhang*. "Spatiotemporal precise optical manipulation of intracellular molecular activities", Advanced Science, 2307342 (2024) Link
Software-assisted RPOC
B. Dong, R. M. Everly, S. Mahapatra, M. S. Carlsen, S. Ma, and C. Zhang*. "Unleashing precision and freedom of optical manipulation: Software-aided real-time precision opto-control of intracellular molecular activities and cell functions". BioRxiv (2024): https://www.biorxiv.org/content/10.1101/2024.02.09.579709v1
Applications
S. Mahapatra, S. Ma, B. Dong, and C. Zhang*. "Quantification of cellular phototoxicity of organelle stains by the dynamics of microtubule polymerization" BioRxiv (2024): https://www.biorxiv.org/content/10.1101/2024.01.17.576021v1
J. Zhang, H. Lin, J. Xu, M Zhang, X. Ge, C. Zhang, W. E. Huang, and J. X. Cheng*. "High-throughput single-cell sorting by stimulated Raman-activated cell ejection" Science Advances, In Press (2024): https://doi.org/10.1101/2023.10.16.562526